Motif ID: SOX{8,9,10}.p2

Z-value: 1.563


Transcription factors associated with SOX{8,9,10}.p2:

Gene SymbolEntrez IDGene Name
Sox10 20665 SRY-box containing gene 10
Sox8 20681 SRY-box containing gene 8
Sox9 20682 SRY-box containing gene 9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox9chr11_+_1126435010.281.7e-04Click!
Sox8chr17_-_257075990.199.4e-03Click!
Sox10chr15_-_789947530.046.1e-01Click!


Activity profile for motif SOX{8,9,10}.p2.

activity profile for motif SOX{8,9,10}.p2


Sorted Z-values histogram for motif SOX{8,9,10}.p2

Sorted Z-values for motif SOX{8,9,10}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX{8,9,10}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_43552694 19.994 NM_009468
Dpysl3
dihydropyrimidinase-like 3
chr1_-_82232392 17.466 Irs1
insulin receptor substrate 1
chr8_+_125935470 16.101 Tubb3
tubulin, beta 3
chr9_-_83040061 15.577 NM_026122
NM_175074
Hmgn3

high mobility group nucleosomal binding domain 3

chr1_+_45401659 14.393 Col3a1
collagen, type III, alpha 1
chr3_-_57651621 14.118 NM_019410
Pfn2
profilin 2
chr19_-_40588193 13.676 Sorbs1
sorbin and SH3 domain containing 1
chr15_+_98465193 13.445 NM_007581
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr1_+_45401303 13.047 Col3a1
collagen, type III, alpha 1
chr3_+_121160714 13.035 Cnn3
calponin 3, acidic
chr10_-_36858671 12.881 NM_008538
Marcks
myristoylated alanine rich protein kinase C substrate
chr17_-_35975075 12.560 Tubb5
tubulin, beta 5
chr19_-_15999377 12.311 NM_177420
Psat1
phosphoserine aminotransferase 1
chr9_-_49311823 12.174 Ncam1
neural cell adhesion molecule 1
chr4_+_134024234 12.156 NM_019641
Stmn1
stathmin 1
chr19_-_40588235 12.140 Sorbs1
sorbin and SH3 domain containing 1
chr6_+_122463595 11.716 Mfap5
microfibrillar associated protein 5
chr1_-_194677940 11.469 NM_001177794
Sertad4
SERTA domain containing 4
chr19_+_44368557 11.400 Scd2
stearoyl-Coenzyme A desaturase 2
chr18_-_16967754 10.953 Cdh2
cadherin 2
chr12_+_110784600 10.896 Meg3
maternally expressed 3
chr16_-_85080242 10.827 App
amyloid beta (A4) precursor protein
chr11_-_75236085 10.719 NM_011340
Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr11_-_75236018 10.461 Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr10_+_85763267 10.425 Timp3
tissue inhibitor of metalloproteinase 3
chr2_+_152561983 10.399 NM_010495
Id1
inhibitor of DNA binding 1
chr3_+_7503409 10.357 NM_173181
Fam164a
family with sequence similarity 164, member A
chr8_+_26629868 10.338 Fgfr1
fibroblast growth factor receptor 1
chr2_-_125331264 10.286 Fbn1
fibrillin 1
chr19_-_40588219 10.285 NM_178362
Sorbs1
sorbin and SH3 domain containing 1
chr12_-_103057112 10.220 Fbln5
fibulin 5
chr15_+_98465328 10.138 Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr11_+_44431601 10.091 NM_007897
Ebf1
early B-cell factor 1
chrX_+_54032914 10.026 Fhl1
four and a half LIM domains 1
chr16_-_22439642 10.016 NM_023794
Etv5
ets variant gene 5
chr1_+_12682572 9.988 Sulf1
sulfatase 1
chr8_+_125935441 9.873 NM_023279
Tubb3
tubulin, beta 3
chr10_+_85763287 9.737 Timp3
tissue inhibitor of metalloproteinase 3
chr3_+_90280032 9.698 NM_026374
Ilf2
interleukin enhancer binding factor 2
chr18_+_37839910 9.660 NM_033574
Pcdhgb1
protocadherin gamma subfamily B, 1
chr19_-_10944196 9.633 NM_133804
Tmem132a
transmembrane protein 132A
chr6_+_122463663 9.579 NM_015776
Mfap5
microfibrillar associated protein 5
chr12_+_76409299 9.493 NM_023275
Rhoj
ras homolog gene family, member J
chr7_+_19876447 9.474 NM_001025364
Rtn2
reticulon 2 (Z-band associated protein)
chr5_+_143722032 9.418 NM_007984
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr13_-_60278859 9.348 NM_008086
Gas1
growth arrest specific 1
chr12_+_110783786 9.326 Meg3
maternally expressed 3
chr10_+_85763294 9.190 Timp3
tissue inhibitor of metalloproteinase 3
chr7_+_89319717 9.169 NM_017400
Sh3gl3
SH3-domain GRB2-like 3
chr11_-_95936914 9.087 NM_001161419
NM_007506
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr12_-_103056971 9.053 Fbln5
fibulin 5
chr9_+_106356125 8.937 NM_021567
Pcbp4
poly(rC) binding protein 4
chr18_-_16966954 8.926 Cdh2
cadherin 2
chr10_+_85763303 8.913 Timp3
tissue inhibitor of metalloproteinase 3
chr6_+_34548512 8.907 Cald1
caldesmon 1
chr3_+_121426422 8.907 NM_010171
F3
coagulation factor III
chr8_+_26629736 8.857 Fgfr1
fibroblast growth factor receptor 1
chr5_+_37637027 8.829 NM_007765
Crmp1
collapsin response mediator protein 1
chr11_-_22185840 8.740 NM_153078
Ehbp1
EH domain binding protein 1
chr11_+_29592897 8.738 NM_194052
NM_194053
NM_194054
Rtn4


reticulon 4


chr18_-_33623287 8.736 NM_053078
D0H4S114
DNA segment, human D4S114
chr19_+_5474801 8.640 Efemp2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr18_+_37906739 8.632 NM_033593
Pcdhga10
protocadherin gamma subfamily A, 10
chr19_+_44368165 8.623 NM_009128
Scd2
stearoyl-Coenzyme A desaturase 2
chr3_+_90345082 8.601 NM_026416
S100a16
S100 calcium binding protein A16
chr18_+_37901716 8.592 NM_033578
Pcdhgb6
protocadherin gamma subfamily B, 6
chr7_+_89319681 8.561 Sh3gl3
SH3-domain GRB2-like 3
chr16_-_85901362 8.477 NM_011782
Adamts5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
chr11_+_29592946 8.320 Rtn4
reticulon 4
chr12_+_30622876 8.305 NM_181395
Pxdn
peroxidasin homolog (Drosophila)
chr1_+_137625754 8.254 NM_007791
Csrp1
cysteine and glycine-rich protein 1
chr18_-_43597640 8.248 Dpysl3
dihydropyrimidinase-like 3
chr8_+_98226914 8.114 NM_001195006
NM_145602
Ndrg4

N-myc downstream regulated gene 4

chr3_+_145421870 8.112 Ddah1
dimethylarginine dimethylaminohydrolase 1
chr6_-_12699189 8.089 NM_001164805
Thsd7a
thrombospondin, type I, domain containing 7A
chr1_+_172574668 8.007 Olfml2b
olfactomedin-like 2B
chr15_+_98957150 7.960 Spats2
spermatogenesis associated, serine-rich 2
chr15_-_103070263 7.959 Cbx5
chromobox homolog 5 (Drosophila HP1a)
chr17_+_44090139 7.939 NM_030598
Rcan2
regulator of calcineurin 2
chr1_+_172574698 7.903 Olfml2b
olfactomedin-like 2B
chr11_+_32355355 7.828 NM_173784
Ubtd2
ubiquitin domain containing 2
chr2_+_109757803 7.766 NM_172671
Lgr4
leucine-rich repeat-containing G protein-coupled receptor 4
chr2_+_35516774 7.763 Dab2ip
disabled homolog 2 (Drosophila) interacting protein
chr7_-_4465970 7.749 Tnnt1
troponin T1, skeletal, slow
chr19_-_40588297 7.701 NM_009166
Sorbs1
sorbin and SH3 domain containing 1
chr11_-_65601657 7.686 Map2k4
mitogen-activated protein kinase kinase 4
chr18_+_37911236 7.653 NM_033579
Pcdhgb7
protocadherin gamma subfamily B, 7
chr1_+_172574662 7.586 NM_177068
Olfml2b
olfactomedin-like 2B
chr13_-_60278723 7.536 Gas1
growth arrest specific 1
chr8_-_11312686 7.485 Col4a1
collagen, type IV, alpha 1
chr7_-_31230564 7.485 Aplp1
amyloid beta (A4) precursor-like protein 1
chr7_-_31230577 7.443 NM_007467
Aplp1
amyloid beta (A4) precursor-like protein 1
chr11_+_59476016 7.432 Mprip
myosin phosphatase Rho interacting protein
chr19_+_5475020 7.428 Efemp2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr11_-_75236012 7.412 Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr19_+_27292039 7.410 Vldlr
very low density lipoprotein receptor
chr4_+_17780739 7.406 Mmp16
matrix metallopeptidase 16
chr2_-_30329717 7.363 NM_030244
Ier5l
immediate early response 5-like
chr10_+_56097078 7.327 NM_010288
Gja1
gap junction protein, alpha 1
chr12_+_31950097 7.287 NM_008482
Lamb1
laminin B1
chr7_+_138079669 7.281 NM_019564
Htra1
HtrA serine peptidase 1
chr8_-_23296255 7.246 NM_001004140
Ckap2
cytoskeleton associated protein 2
chr18_+_82723920 7.147 Mbp
myelin basic protein
chr18_+_37921454 7.144 NM_033580
Pcdhgb8
protocadherin gamma subfamily B, 8
chr2_+_72244049 7.136 B230120H23Rik
RIKEN cDNA B230120H23 gene
chr13_-_60278447 7.105 Gas1
growth arrest specific 1
chr18_+_82723854 7.068 NM_001025251
NM_001025255
NM_001025256
NM_001025258
NM_001025259
NM_001025254
Mbp





myelin basic protein





chr17_+_44090222 7.065 Rcan2
regulator of calcineurin 2
chr9_+_70526985 7.046 Adam10
a disintegrin and metallopeptidase domain 10
chr11_+_29593657 7.042 NM_194051
Rtn4
reticulon 4
chr5_+_75552144 7.036 NM_001083316
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr13_-_21845695 7.010 NM_178183
Hist1h2ak
histone cluster 1, H2ak
chr10_+_85763156 6.965 NM_011595
Timp3
tissue inhibitor of metalloproteinase 3
chr18_+_37849488 6.953 NM_033575
Pcdhgb2
protocadherin gamma subfamily B, 2
chr18_+_82723907 6.950 Mbp
myelin basic protein
chr3_-_145312928 6.933 NM_010516
Cyr61
cysteine rich protein 61
chr3_-_36470882 6.923 Ccna2
cyclin A2
chr6_+_83087016 6.898 NM_009106
NM_133641
Rtkn

rhotekin

chr3_-_36470845 6.878 Ccna2
cyclin A2
chr18_-_16967100 6.844 Cdh2
cadherin 2
chr17_+_44090341 6.841 Rcan2
regulator of calcineurin 2
chr8_+_11312828 6.817 NM_009932
Col4a2
collagen, type IV, alpha 2
chr15_-_98783909 6.807 NM_011653
Tuba1a
tubulin, alpha 1A
chr12_+_41172639 6.798 NM_172803
Dock4
dedicator of cytokinesis 4
chr14_-_71018208 6.793 Epb4.9
erythrocyte protein band 4.9
chr12_-_81744771 6.752 NM_007951
Erh
enhancer of rudimentary homolog (Drosophila)
chr7_-_31230463 6.743 Aplp1
amyloid beta (A4) precursor-like protein 1
chr16_+_23146631 6.738 Adipoq
adiponectin, C1Q and collagen domain containing
chr13_+_113254277 6.669 NM_010560
Il6st
interleukin 6 signal transducer
chr11_+_59475986 6.645 NM_012027
NM_201245
Mprip

myosin phosphatase Rho interacting protein

chr8_-_87323958 6.571 Nfix
nuclear factor I/X
chr17_+_87506971 6.476 NM_019654
Socs5
suppressor of cytokine signaling 5
chr12_+_31950252 6.443 Lamb1
laminin B1
chr18_+_37890662 6.439 NM_033577
Pcdhgb5
protocadherin gamma subfamily B, 5
chr13_-_60278558 6.405 Gas1
growth arrest specific 1
chr8_+_120807674 6.359 Cdh13
cadherin 13
chr18_+_37880036 6.320 NM_033576
Pcdhgb4
protocadherin gamma subfamily B, 4
chr14_+_21748602 6.313 Vcl
vinculin
chr7_-_20300595 6.308 Tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr8_-_11312729 6.242 NM_009931
Col4a1
collagen, type IV, alpha 1
chr8_+_120807621 6.220 NM_019707
Cdh13
cadherin 13
chr9_-_70269246 6.215 Ccnb2
cyclin B2
chr2_+_158593806 6.211 NM_027975
Fam83d
family with sequence similarity 83, member D
chr7_-_128125714 6.181 NM_007672
Cdr2
cerebellar degeneration-related 2
chr5_+_111846284 6.167 Mn1
meningioma 1
chr3_-_89222140 6.166 NM_016904
Cks1b
CDC28 protein kinase 1b
chr1_-_94076857 6.165 Hdac4
histone deacetylase 4
chr14_+_63754443 6.162 Ctsb
cathepsin B
chr1_-_156993820 6.152 NM_008209
Mr1
major histocompatibility complex, class I-related
chr3_-_36470904 6.097 NM_009828
Ccna2
cyclin A2
chr7_+_119167034 5.938 Usp47
ubiquitin specific peptidase 47
chr7_-_89079168 5.920 Hdgfrp3
hepatoma-derived growth factor, related protein 3
chr14_+_121434765 5.917 NM_134082
Farp1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr3_-_151873041 5.813 Dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr2_+_26171051 5.785 NM_153410
Gpsm1
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr15_-_43002356 5.752 NM_172815
Rspo2
R-spondin 2 homolog (Xenopus laevis)
chr8_+_55635683 5.739 NM_029569
Asb5
ankyrin repeat and SOCs box-containing 5
chr1_+_12708582 5.649 NM_172294
Sulf1
sulfatase 1
chr4_-_134828699 5.635 Clic4
chloride intracellular channel 4 (mitochondrial)
chr11_+_115243203 5.575 NM_001080929
Cdr2l
cerebellar degeneration-related protein 2-like
chr12_-_103677867 5.568 NM_011175
Lgmn
legumain
chr4_+_48598013 5.558 NM_021436
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_+_26171073 5.551 Gpsm1
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr13_-_34222209 5.549 NM_023716
Tubb2b
tubulin, beta 2B
chr12_+_96930429 5.524 NM_201518
Flrt2
fibronectin leucine rich transmembrane protein 2
chr1_-_173126368 5.485 NM_025557
Pcp4l1
Purkinje cell protein 4-like 1
chr5_+_37633353 5.420 Crmp1
collapsin response mediator protein 1
chr3_+_121670737 5.362 Arhgap29
Rho GTPase activating protein 29
chr11_-_6344445 5.343 NM_029938
H2afv
H2A histone family, member V
chr4_+_129190872 5.294 Marcksl1
MARCKS-like 1
chr2_+_156246644 5.291 NM_001003815
NM_013510
Epb4.1l1

erythrocyte protein band 4.1-like 1

chr8_+_26629214 5.270 NM_001079908
NM_001079909
NM_010206
Fgfr1


fibroblast growth factor receptor 1


chr2_-_73418334 5.267 NM_007389
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr14_+_55050530 5.264 Mmp14
matrix metallopeptidase 14 (membrane-inserted)
chr4_+_13670582 5.218 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_54543167 5.197 Fkbp14
FK506 binding protein 14
chr13_+_113657736 5.176


chr17_+_44090192 5.173 Rcan2
regulator of calcineurin 2
chr3_-_95032039 5.135 Mllt11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr3_-_57651409 5.130 Pfn2
profilin 2
chr9_-_29219306 5.104 Ntm
neurotrimin
chr10_-_61246611 5.090 NM_207000
H2afy2
H2A histone family, member Y2
chr2_-_181049204 5.089 NM_009133
Stmn3
stathmin-like 3
chr8_+_108939247 5.069 Zfp90
zinc finger protein 90
chr15_-_76853069 5.052 NM_001164048
NM_001164047
Mb

myoglobin

chr6_+_22825464 5.036 NM_001081306
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr8_-_48373564 5.027 Stox2
storkhead box 2
chrX_+_155897136 5.013 Mtap7d2
MAP7 domain containing 2
chr10_+_125403274 5.007 NM_177152
Lrig3
leucine-rich repeats and immunoglobulin-like domains 3
chr12_-_73337534 4.995 Rtn1
reticulon 1
chr10_-_75395207 4.980 NM_008606
Mmp11
matrix metallopeptidase 11
chr8_+_55635768 4.947 Asb5
ankyrin repeat and SOCs box-containing 5
chr19_-_44470218 4.918 Scd1
stearoyl-Coenzyme A desaturase 1
chr19_-_42160732 4.914 NM_198108
Morn4
MORN repeat containing 4
chr2_+_31951030 4.913 Ppapdc3
phosphatidic acid phosphatase type 2 domain containing 3
chrX_+_104115963 4.880 NM_175271
Lpar4
lysophosphatidic acid receptor 4
chr4_-_125933482 4.875 NM_001145970
NM_144941
Mtap7d1

microtubule-associated protein 7 domain containing 1

chr6_-_54543121 4.874 NM_153573
Fkbp14
FK506 binding protein 14
chr3_-_88905775 4.870 NM_134469
Fdps
farnesyl diphosphate synthetase
chr11_+_66984528 4.842 NM_001039545
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.67 3.91e-21 GO:0032502 developmental process
1.68 1.08e-19 GO:0007275 multicellular organismal development
1.72 1.37e-19 GO:0048856 anatomical structure development
1.69 3.62e-19 GO:0016043 cellular component organization
1.66 1.97e-18 GO:0071840 cellular component organization or biogenesis
1.80 4.54e-18 GO:0071842 cellular component organization at cellular level
1.76 3.25e-17 GO:0071841 cellular component organization or biogenesis at cellular level
1.73 3.64e-17 GO:0048731 system development
1.71 3.30e-14 GO:0048523 negative regulation of cellular process
2.75 7.24e-14 GO:0007010 cytoskeleton organization
1.66 1.42e-13 GO:0048519 negative regulation of biological process
1.99 1.56e-13 GO:0007399 nervous system development
1.69 6.78e-12 GO:0030154 cell differentiation
2.14 1.23e-11 GO:0022008 neurogenesis
1.82 1.28e-11 GO:0006996 organelle organization
1.66 2.39e-11 GO:0048869 cellular developmental process
2.16 3.01e-11 GO:0048699 generation of neurons
3.31 8.15e-11 GO:0030036 actin cytoskeleton organization
1.80 2.51e-10 GO:0009653 anatomical structure morphogenesis
3.17 2.70e-10 GO:0030029 actin filament-based process
1.94 9.13e-08 GO:0051128 regulation of cellular component organization
3.90 1.51e-07 GO:0051146 striated muscle cell differentiation
1.47 4.97e-07 GO:0048522 positive regulation of cellular process
1.88 8.00e-07 GO:0048468 cell development
1.57 8.74e-07 GO:0048513 organ development
3.25 1.76e-06 GO:0042692 muscle cell differentiation
1.34 2.17e-06 GO:0019222 regulation of metabolic process
2.25 2.70e-06 GO:0048666 neuron development
2.11 3.70e-06 GO:0072358 cardiovascular system development
2.11 3.70e-06 GO:0072359 circulatory system development
4.60 4.40e-06 GO:0055002 striated muscle cell development
2.07 5.82e-06 GO:0030182 neuron differentiation
1.41 6.40e-06 GO:0048518 positive regulation of biological process
2.58 1.00e-05 GO:0061061 muscle structure development
3.41 1.02e-05 GO:0003012 muscle system process
1.96 1.27e-05 GO:0007155 cell adhesion
2.35 1.69e-05 GO:0031175 neuron projection development
1.95 1.86e-05 GO:0022610 biological adhesion
2.66 2.06e-05 GO:0051129 negative regulation of cellular component organization
1.78 2.07e-05 GO:2000026 regulation of multicellular organismal development
2.64 2.36e-05 GO:0000087 M phase of mitotic cell cycle
1.69 4.82e-05 GO:0050793 regulation of developmental process
4.04 5.68e-05 GO:0055001 muscle cell development
1.56 6.92e-05 GO:0051239 regulation of multicellular organismal process
2.28 6.95e-05 GO:0050767 regulation of neurogenesis
1.33 6.98e-05 GO:0031323 regulation of cellular metabolic process
2.43 7.05e-05 GO:0045664 regulation of neuron differentiation
2.20 7.08e-05 GO:0051960 regulation of nervous system development
1.94 9.96e-05 GO:0071844 cellular component assembly at cellular level
2.57 1.17e-04 GO:0000280 nuclear division
2.57 1.17e-04 GO:0007067 mitosis
2.53 1.21e-04 GO:0048285 organelle fission
1.12 1.21e-04 GO:0009987 cellular process
2.03 1.31e-04 GO:0032989 cellular component morphogenesis
4.10 2.12e-04 GO:0051494 negative regulation of cytoskeleton organization
1.83 3.40e-04 GO:0019220 regulation of phosphate metabolic process
1.83 3.40e-04 GO:0051174 regulation of phosphorus metabolic process
2.08 3.81e-04 GO:0060284 regulation of cell development
1.70 4.41e-04 GO:0009888 tissue development
2.10 4.82e-04 GO:0000278 mitotic cell cycle
1.72 5.68e-04 GO:0009790 embryo development
1.33 5.95e-04 GO:0051179 localization
1.30 7.07e-04 GO:0080090 regulation of primary metabolic process
2.41 7.17e-04 GO:0007017 microtubule-based process
1.72 7.18e-04 GO:0007049 cell cycle
1.31 7.85e-04 GO:0060255 regulation of macromolecule metabolic process
1.68 1.05e-03 GO:0022607 cellular component assembly
1.83 1.09e-03 GO:0040011 locomotion
2.14 1.61e-03 GO:0001944 vasculature development
2.11 1.80e-03 GO:0051301 cell division
3.10 2.38e-03 GO:0006936 muscle contraction
3.52 2.83e-03 GO:0007015 actin filament organization
1.16 3.21e-03 GO:0050789 regulation of biological process
1.19 3.37e-03 GO:0044237 cellular metabolic process
1.68 3.43e-03 GO:0045595 regulation of cell differentiation
1.88 3.52e-03 GO:0030030 cell projection organization
1.85 3.90e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.47 4.24e-03 GO:0065009 regulation of molecular function
2.15 4.35e-03 GO:0033043 regulation of organelle organization
2.56 4.37e-03 GO:0051493 regulation of cytoskeleton organization
5.48 4.80e-03 GO:0031032 actomyosin structure organization
1.75 4.90e-03 GO:0042325 regulation of phosphorylation
2.09 5.45e-03 GO:0051270 regulation of cellular component movement
2.97 5.50e-03 GO:0010639 negative regulation of organelle organization
1.58 5.51e-03 GO:0044085 cellular component biogenesis
2.04 6.05e-03 GO:0000279 M phase
2.30 6.11e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.14 6.11e-03 GO:0030334 regulation of cell migration
1.15 6.65e-03 GO:0065007 biological regulation
1.84 7.08e-03 GO:0043009 chordate embryonic development
1.77 8.14e-03 GO:0022402 cell cycle process
2.11 8.81e-03 GO:2000145 regulation of cell motility
1.99 9.89e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.01 9.95e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.59 1.09e-02 GO:0042127 regulation of cell proliferation
4.68 1.11e-02 GO:0032272 negative regulation of protein polymerization
1.82 1.13e-02 GO:0009792 embryo development ending in birth or egg hatching
1.45 1.38e-02 GO:0023051 regulation of signaling
2.48 1.85e-02 GO:0060537 muscle tissue development
1.49 1.97e-02 GO:0009966 regulation of signal transduction
5.91 2.05e-02 GO:0030239 myofibril assembly
1.53 2.19e-02 GO:0032879 regulation of localization
1.52 2.47e-02 GO:0010646 regulation of cell communication
2.08 2.90e-02 GO:0001501 skeletal system development
2.04 2.95e-02 GO:0001568 blood vessel development
2.07 3.17e-02 GO:0007507 heart development
1.17 3.20e-02 GO:0044238 primary metabolic process
1.90 3.38e-02 GO:0016477 cell migration
1.39 3.48e-02 GO:0042221 response to chemical stimulus
1.85 3.67e-02 GO:0040008 regulation of growth
3.91 4.11e-02 GO:0031333 negative regulation of protein complex assembly
3.91 4.11e-02 GO:0048747 muscle fiber development
1.52 4.12e-02 GO:0051641 cellular localization
2.38 4.17e-02 GO:0010975 regulation of neuron projection development
1.68 4.24e-02 GO:0009887 organ morphogenesis
3.06 4.43e-02 GO:0007018 microtubule-based movement
2.57 4.53e-02 GO:0046034 ATP metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.31 2.45e-34 GO:0005622 intracellular
1.32 9.13e-34 GO:0044424 intracellular part
1.40 4.25e-30 GO:0005737 cytoplasm
1.87 1.29e-25 GO:0043228 non-membrane-bounded organelle
1.87 1.29e-25 GO:0043232 intracellular non-membrane-bounded organelle
1.31 1.29e-22 GO:0043226 organelle
1.31 2.64e-22 GO:0043229 intracellular organelle
2.01 3.12e-19 GO:0005856 cytoskeleton
1.38 1.41e-14 GO:0044444 cytoplasmic part
1.94 2.92e-13 GO:0000267 cell fraction
1.43 4.84e-13 GO:0044422 organelle part
1.43 2.23e-12 GO:0044446 intracellular organelle part
2.01 1.62e-11 GO:0044430 cytoskeletal part
1.25 1.94e-11 GO:0043231 intracellular membrane-bounded organelle
1.24 2.06e-11 GO:0043227 membrane-bounded organelle
1.52 3.86e-11 GO:0043234 protein complex
1.47 4.01e-11 GO:0032991 macromolecular complex
1.11 5.55e-11 GO:0005623 cell
1.11 5.55e-11 GO:0044464 cell part
1.35 1.93e-10 GO:0005634 nucleus
2.88 2.07e-10 GO:0015629 actin cytoskeleton
1.71 9.72e-10 GO:0005829 cytosol
1.86 2.16e-08 GO:0005626 insoluble fraction
1.81 4.74e-07 GO:0005624 membrane fraction
2.57 8.01e-07 GO:0005874 microtubule
3.38 1.98e-06 GO:0043292 contractile fiber
1.69 2.15e-06 GO:0042995 cell projection
1.96 6.54e-06 GO:0015630 microtubule cytoskeleton
1.95 7.63e-06 GO:0043005 neuron projection
3.33 9.03e-06 GO:0044420 extracellular matrix part
2.22 1.07e-05 GO:0005625 soluble fraction
3.29 2.12e-05 GO:0030016 myofibril
1.49 3.22e-05 GO:0070013 intracellular organelle lumen
1.49 3.22e-05 GO:0031974 membrane-enclosed lumen
1.54 3.46e-05 GO:0031981 nuclear lumen
1.48 3.48e-05 GO:0044428 nuclear part
1.49 3.64e-05 GO:0043233 organelle lumen
3.30 6.56e-05 GO:0044449 contractile fiber part
2.19 7.31e-05 GO:0031012 extracellular matrix
3.02 7.79e-05 GO:0005912 adherens junction
1.82 8.81e-05 GO:0030054 cell junction
2.23 1.04e-04 GO:0048471 perinuclear region of cytoplasm
2.14 1.21e-04 GO:0044297 cell body
2.87 1.47e-04 GO:0070161 anchoring junction
2.15 1.65e-04 GO:0043025 neuronal cell body
2.24 1.69e-04 GO:0005578 proteinaceous extracellular matrix
1.91 2.38e-04 GO:0045202 synapse
4.40 6.69e-04 GO:0042641 actomyosin
2.46 8.20e-04 GO:0045121 membrane raft
3.31 1.23e-03 GO:0005924 cell-substrate adherens junction
3.14 1.59e-03 GO:0030017 sarcomere
1.26 2.15e-03 GO:0071944 cell periphery
3.08 3.66e-03 GO:0030055 cell-substrate junction
2.22 3.98e-03 GO:0016323 basolateral plasma membrane
4.23 5.82e-03 GO:0001725 stress fiber
3.11 9.62e-03 GO:0005925 focal adhesion
2.08 9.78e-03 GO:0045177 apical part of cell
3.75 1.05e-02 GO:0005884 actin filament
1.51 1.06e-02 GO:0044421 extracellular region part
1.91 1.16e-02 GO:0044456 synapse part
6.74 1.24e-02 GO:0031672 A band
3.94 1.28e-02 GO:0032432 actin filament bundle
3.49 1.29e-02 GO:0005901 caveola
1.85 1.31e-02 GO:0005730 nucleolus
3.03 1.36e-02 GO:0005604 basement membrane
1.35 1.43e-02 GO:0044459 plasma membrane part
1.80 1.45e-02 GO:0044427 chromosomal part
1.76 1.61e-02 GO:0005694 chromosome
1.23 2.14e-02 GO:0005886 plasma membrane
2.00 2.27e-02 GO:0030424 axon
11.55 4.54e-02 GO:0030934 anchoring collagen
3.11 4.92e-02 GO:0031674 I band

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.59 4.54e-37 GO:0005515 protein binding
1.31 2.71e-32 GO:0005488 binding
2.56 5.33e-14 GO:0008092 cytoskeletal protein binding
2.42 9.48e-12 GO:0019904 protein domain specific binding
2.79 4.59e-10 GO:0003779 actin binding
1.81 1.79e-06 GO:0019899 enzyme binding
3.19 6.99e-06 GO:0005539 glycosaminoglycan binding
3.04 7.64e-06 GO:0001871 pattern binding
3.04 7.64e-06 GO:0030247 polysaccharide binding
3.26 2.31e-04 GO:0008201 heparin binding
1.65 6.48e-04 GO:0030234 enzyme regulator activity
3.78 8.54e-04 GO:0019902 phosphatase binding
1.84 1.00e-03 GO:0005509 calcium ion binding
1.37 1.74e-03 GO:0000166 nucleotide binding
2.02 6.49e-03 GO:0019900 kinase binding
1.38 6.94e-03 GO:0017076 purine nucleotide binding
1.38 8.28e-03 GO:0032555 purine ribonucleotide binding
1.38 8.56e-03 GO:0032553 ribonucleotide binding
1.38 9.24e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.40 1.67e-02 GO:0030554 adenyl nucleotide binding
1.88 1.77e-02 GO:0032403 protein complex binding
1.41 1.97e-02 GO:0005524 ATP binding
1.40 2.00e-02 GO:0032559 adenyl ribonucleotide binding
7.88 2.35e-02 GO:0003785 actin monomer binding
2.01 3.74e-02 GO:0019901 protein kinase binding
2.33 3.98e-02 GO:0004721 phosphoprotein phosphatase activity
1.47 4.12e-02 GO:0005102 receptor binding
7.22 4.43e-02 GO:0005159 insulin-like growth factor receptor binding
3.41 4.70e-02 GO:0019903 protein phosphatase binding